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WebNov 29, 2010 · Generally the drug lowers blood pressure. Provided you sleep well. Because this medication makes one sleepy it causes fatigue in the body . Fatigue … WebNov 15, 2024 · Clonidine is used to treat high blood pressure, but it also works as a mild sedative. It has been used to manage symptoms of alcohol, opioid and Lyrica withdrawal and can help to manage the agitation due to withdrawal. 2. Dexmedetomidine is another prescription medication with similar effects to clonidine. WebAug 13, 2024 · Diuretics are generally safe. Side effects include increased urination and sodium loss. Diuretics can also affect blood potassium levels. If you take a thiazide diuretic, your potassium level can drop too low (hypokalemia), which can cause life-threatening problems with your heartbeat. de thi online lop 3