WebConnective tissue growth factor (CTGF), also termed fisp12, β IG-M2, and IGF-BP8, is a secreted cysteine-rich growth factor that belongs to the CCN (cyr61, CTGF, nov) family. It was first isolated in 1991 from serum-stimulated NIH3T3 cells and named fisp12 (fibroblast-inducible secreted protein-12). The term ‘connective tissue growth factor ... WebJun 26, 2024 · As a secreted protein, CTGF exerts autocrine and paracrine actions because it localizes not only within the interstitial ECM but also pericellularly, due to its heparin-binding activity (Kireeva et al., 1997).To gain new insights into the function of vascular cell-derived CTGF, we examined the retinal vascular changes associated with global, EC-, or …
CYR61/CCN1 Regulates dCK and CTGF and Causes Gemcitabine …
WebDec 10, 2024 · By examining multiple independent modes of cellular injury, we found that CTGF and Cyr61 expression are downregulated only when podocytes were exposed to molecules known to disrupt the cell’s mechanical integrity or cytoskeletal structure. To our knowledge, this is the first report that the YAP-TEAD1 signaling axis is disrupted when … Web在sh-g3bp2 huvecs中,yap下游基因(包括ctgf,cyr61和ankrd1,)的rna表达水平显著降低(图4 g)。此外,yap抑制剂维替泊芬不能降低oss诱导的g3bp2的表达水平(图4 h),但可显著降低yap靶向下游基因的mrna表达水平,包括ctgf、cyr61、vcam-1 … devon fielding basketball offers
Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in …
WebYAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα. Hyungjoo Kim. 1, Seogho Son1, Yunhyo Ko1, Jeong Eon Lee3, Sangmin Kim3 ... WebJun 20, 2007 · Our results suggest that Cyr61, CTGF, and WISP-1 might be implicated in the development and progression of primary lung cancers, and their levels might serve as valuable prognostic markers, as well as potential targets for therapeutic intervention. WebApr 12, 2024 · Intracavernosal pressure/mean arterial pressure (ICP/MAP) was measured 14 and 28 days after treatment. Penile tissue specimens were collected for pathological examination, and the changes in YAP, TAZ, CTGF, CYR61, LATS1, and p38 MAPK expression levels were assessed by Western blot, RT–qPCR and immunological … devon federation wi