WebA 10 mM solution of NNDHA was used to ion pair with the phosphonate compound for increased chromatographic retention. This enabled isocratic separation of risedronate, pamidronate and alendronate in less than 6 minutes using a standard column configuration. In this case, the 1 mL/min column eluent going to the mass spectrometer source was split … Webphosphonate. 音标:/'fɔsfəuneit/ 生词本: 添加笔记:. 有奖纠错. 划词. 英汉-汉英词典. 词组搭配. 英语百科.
Prodrugs of Phosphonates, Phosphinates, and Phosphates …
WebPhosphonate. Phosphonates or Phosphonic acids are organic compounds containing one or more C-PO (OH) 2 or C-PO (OR) 2 (with R= alkyl, aryl) groups. Bisphosphonates were first synthesized in 1897 by Von Baeyer and Hofmann. An example of such a bisphosphonate is HEDP. Since the work of Schwarzenbach in 1949, phosphonic acids are known as ... Webnoun. phos· pho· nate ˈfäs-fə-ˌnāt. : a salt or ester of a phosphonic acid. great explorers 5
Phosphonates Definition & Meaning Merriam-Webster Medical
Webphosphonates which are used to make a variety of end products such as stabilizers, flame retardants and antioxidants. P0Cl 3 Phosphorous oxichloride Reactive chlorinating and phosphorylating intermediate product Base stock in the production of organic phosphites, phosphates and phosphonates which are used to make a variety of end products Webphosphonate, phosphonate, or phosphate functional group is limited by their inadequate membrane permeation and oral absorption. Phosphonate, phosphinate, and phosphate groups carry one or two negative charges at physio-logical pH values making them very polar (Figure 1). This high polarity is the basis for many deficiencies in terms of drug ... WebJan 1, 2024 · Phosphite. Alkali metal salt of phosphorous acid. The most common phosphite is potassium phosphite, and is made by mixing a solution of potassium … flip short edge vs long edge